Important Safety Information

Start your Keveyis Journey

Reimagine Life with Primary Periodic Paralysis

KEVEYIS® is a daily pill proven to treat Primary Periodic Paralysis (PPP).1
Discover your KEVEYIS journey

How Keveyis can help you

Gain greater control over PPP

When you live with PPP, there’s a lot you can’t control. But KEVEYIS can help. It’s the first FDA-approved treatment for PPP proven to reduce the number, severity and duration of PPP episodes.1,2

In a clinical study, people taking KEVEYIS reported:1,2*

  • PPP episodes decreased
    Patients taking KEVEYIS had fewer episodes.
  • PPP episodes were shorter
    When patients taking KEVEYIS did have episodes, they didn’t last as long.
  • PPP episodes were not as severe
    Patients taking KEVEYIS reported that their episodes were not as severe.
See the results

“Having better control over my PPP symptoms has meant I can engage more fully in my life.”

Janine, KEVEYIS Patient and PPP Mentor

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“I assumed my first call with my Patient Access Manager was only for educational purposes, but after I talked to him, I realized how much better I was feeling emotionally, just being able to have contact with someone who understood what I was going through.”

Dennis, KEVEYIS Patient and PPP Mentor

Get support

Find the support you need — right here

Managing PPP takes more than medication alone. We’ve been committed to supporting the PPP community for years. Through
Xeris CareConnection™, you can access a range of free support services. We’re not just experts — we’re your advocates.

  • Patient Access Managers
    A dedicated, one-on-one resource who can help you navigate life with PPP, from navigating insurance coverage and calling the pharmacy to providing PPP education.
  • Patient Mentors through PPP Mentor Connect™
    Real patients with PPP who currently take KEVEYIS and can share their experience with you.
Sign up for support

DISEASE OVERVIEW

What is PPP?

PPP is a rare genetic condition that impacts your muscles and causes episodes of muscle weakness — and even temporary paralysis.3,4 The road to diagnosis can be difficult, and it’s often mistaken for other health issues.3,4
Learn more about PPP

PATIENT TESTIMONIALS

Real KEVEYIS stories

You don’t have to face PPP alone. Welcome to your KEVEYIS community. Hear from people who have experienced the benefits — and want to help.
Paul
On KEVEYIS since 2017
“I went from about one [attack] a week to one a month since starting KEVEYIS.”

Paul
KEVEYIS patient
Hear more about Paul ➞
Kirsten
On KEVEYIS since 2016
“After starting KEVEYIS I have no attacks of full body paralysis.”

Kirsten
KEVEYIS patient
Hear more about Kirsten ➞
Dennis
On KEVEYIS since 2016
“Before KEVEYIS, I was having a lot of episodes…it was horrible. [After starting KEVEYIS], I haven’t had a serious attack in years.”

Dennis
KEVEYIS patient
Hear more about Dennis ➞
Janine
On KEVEYIS since 2016
“Having more control over my symptoms on KEVEYIS I feel more confident, more independent.”

Janine
KEVEYIS patient
Hear more about Janine ➞
Explore patient stories

Take the next step

Get customized support for your KEVEYIS journey. Simply fill out the information and a Patient Access Manager will contact you. They will walk you through the entire process, from diagnosis to treatment and beyond.

By submitting this form, I understand I am giving Xeris Pharmaceuticals, Inc., its affiliates, and business partners permission to use the personal information provided in this registration form to contact me by the following methods, but not limited to: mail, email, telephone call or in-person about disease and product information, disease or product-related events, support services, market research, and to share promotional and marketing information. By submitting this form, I consent to these uses and am confirming that I have read and agree to the Xeris Pharmaceuticals® Terms of Use and Privacy Statement. I understand I can unsubscribe by clicking on the unsubscribe link in future communications or by sending a letter with my full contact information (eg, name, address, email, phone, etc) to Xeris CareConnection™ Patient Support Services, 1375 W Fulton Street, Suite 1300, Chicago, IL 60607.

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References

  1. KEVEYIS [package insert]. Chicago, IL; Xeris Pharmaceuticals.
  2. Sansone VA, Burge J, McDermott MP, et al; for the Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology. 2016;86:1408-1416.
  3. Charles G, Zheng C, Lehmann-Horn F, Jurkat-Rott K, Levitt J. Characterization of hyperkalemic periodic paralysis: a survey of genetically diagnosed individuals. J Neurol. 2013;260:2606-2613.
  4. Statland JM, Fontaine B, Hanna MG, et al. Review of the diagnosis and treatment of periodic paralysis. Muscle Nerve. 2018;57:522-530.

INDICATION AND IMPORTANT SAFETY INFORMATION — READ MORE

Indication and Important Safety Information

 

What is KEVEYIS?

KEVEYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.

 

What should you tell your healthcare provider before taking KEVEYIS?

Tell your doctor if you are allergic to dichlorphenamide or other sulfa drugs; if you take high doses of aspirin, or if you have lung or liver disease; if you are pregnant, plan to become pregnant, or are breastfeeding or plan to breastfeed.

 

What should you know about KEVEYIS?

  • Severe allergic and other reactions have happened with sulfonamides (drugs such as KEVEYIS) and have sometimes been fatal. Stop taking KEVEYIS at the first sign of skin rash, swelling, difficulty breathing, or any other unexpected side effect or reaction, and call 911 right away.
  • Tell your healthcare provider if you take aspirin or if another healthcare provider instructs you to begin taking aspirin. High doses of aspirin should not be taken with KEVEYIS.
  • KEVEYIS can cause your body to lose potassium, which can lead to heart problems. Your healthcare provider will measure the potassium levels in your blood before you start treatment and at certain times during treatment.
  • Tell your healthcare provider about all other prescription and over-the-counter medicines you take, including supplements, as some medicines can interact with KEVEYIS.
  • While taking KEVEYIS, your body may produce too much acid or may not be able to remove acid from the body. Your healthcare provider may run tests on a regular basis to check for signs of acid buildup.
  • KEVEYIS may increase your risk of falling. Tell your healthcare provider right away if you experience a fall while taking KEVEYIS.
  • The risks of falls and acid buildup are greater in elderly patients.
  • It is not known whether KEVEYIS is safe or effective for people younger than 18 years of age.

 

What are the most common side effects with KEVEYIS?

The most common side effects are a feeling of numbness, tingling or burning (“pins and needles”) in the toes, feet, hands or fingers; trouble with memory or thinking; feeling confused; and unpleasant taste in the mouth.

These are not all of the possible side effects of KEVEYIS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Full Prescribing Information.

Xeris

Keveyis®, Xeris Pharmaceuticals®, Xeris CareConnection™, PPP MentorConnect™, and their associated logos are trademarks owned by or licensed to Xeris Pharmaceuticals, Inc.

FOR PATIENTS

OTHER

Copyright © 2024 Xeris Pharmaceuticals, Inc. All rights reserved.
US-KEV-24-00023 7/2024

Find answers

Take the next step

Get customized support for your KEVEYIS journey. Simply fill out the information and a Patient Access Manager will contact you. They will walk you through the entire process, from diagnosis to treatment and beyond.

By submitting this form, I understand I am giving Xeris Pharmaceuticals, Inc., its affiliates, and business partners permission to use the personal information provided in this registration form to contact me by the following methods, but not limited to: mail, email, telephone call or in-person about disease and product information, disease or product-related events, support services, market research, and to share promotional and marketing information. By submitting this form, I consent to these uses and am confirming that I have read and agree to the Xeris Pharmaceuticals® Terms of Use and Privacy Statement. I understand I can unsubscribe by clicking on the unsubscribe link in future communications or by sending a letter with my full contact information (eg, name, address, email, phone, etc) to Xeris CareConnection™ Patient Support Services, 1375 W Fulton Street, Suite 1300, Chicago, IL 60607.

Thank you!

We’ve received your message and will be in touch shortly.