Important Safety Information

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About KEVEYIS

Gain greater control over Primary Periodic Paralysis with KEVEYIS®

Learn more about PPP

KEVEYIS is proven to treat PPP1,2

KEVEYIS is a daily pill proven to reduce the number, severity and length of PPP episodes in 2 clinical studies.1,2 It’s the first drug approved by the FDA for treatment of PPP.1

When compared with an inactive pill in a 9-week study:

  • Number of episodes decreased1,2
    People taking KEVEYIS had fewer weekly episodes.
  • Episodes were shorter1,2
    When patients taking KEVEYIS did have episodes, they didn’t last as long.
  • Episodes were not as severe1,2
    Patients taking KEVEYIS reported that their episodes were not as severe.
A second study confirmed the results of the first study.3

Taking KEVEYIS

KEVEYIS is a pill that you take by mouth once or twice a day, depending on what your doctor prescribed. Treatment with KEVEYIS is personalized, so your doctor can change your dose to find what’s right for you.1

Before you start KEVEYIS, work with your doctor to set treatment goals to track your progress while on KEVEYIS.1

KEVEYIS common side effects1

It’s normal to experience certain side effects when you start taking KEVEYIS. Some side effects can be resolved with proper techniques or dose adjustment with the help of your doctor.1

Tingling or prickling sensations
(pins and needles)

Confusion or trouble paying attention

Changes in taste

Brain fog

Moving forward with PPP with KEVEYIS

Hear Dennis’s story about how KEVEYIS helped him gain more control over his PPP.

PATIENT TESTIMONIALS

Real KEVEYIS stories

Patients share their experience of taking KEVEYIS for PPP.
Paul
On KEVEYIS since 2017
“I went from about one [attack] a week to one a month since starting KEVEYIS.”

Paul
KEVEYIS patient
Hear more about Paul ➞
Kirsten
On KEVEYIS since 2016
“After starting KEVEYIS I have no attacks of full body paralysis.”

Kirsten
KEVEYIS patient
Hear more about Kirsten ➞
Dennis
On KEVEYIS since 2016
“Before KEVEYIS, I was having a lot of episodes…it was horrible. [After starting KEVEYIS], I haven’t had a serious attack in years.”

Dennis
KEVEYIS patient
Hear more about Dennis ➞
Janine
On KEVEYIS since 2016
“Having more control over my symptoms on KEVEYIS I feel more confident, more independent.”

Janine
KEVEYIS patient
Hear more about Janine ➞

Take the next step

Find out if KEVEYIS is right for you — and see for yourself the difference it can make.

By submitting this form, I understand I am giving Xeris Pharmaceuticals, Inc., its affiliates, and business partners permission to use the personal information provided in this registration form to contact me by the following methods, but not limited to: mail, email, telephone call or in-person about disease and product information, disease or product-related events, support services, market research, and to share promotional and marketing information. By submitting this form, I consent to these uses and am confirming that I have read and agree to the Xeris Pharmaceuticals® Terms of Use and Privacy Statement. I understand I can unsubscribe by clicking on the unsubscribe link in future communications or by sending a letter with my full contact information (eg, name, address, email, phone, etc) to Xeris CareConnection™ Patient Support Services, 1375 W Fulton Street, Suite 1300, Chicago, IL 60607.

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References

  1. KEVEYIS [package insert]. Chicago, IL; Xeris Pharmaceuticals.
  2. Sansone VA, Burge J, McDermott MP, et al; for the Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology. 2016;86:1408-1416.
  3. Tawil R, McDermott MP, Brown R, et al. Randomized trials of dichlorphenamide in the periodic paralyses. Working Group on Periodic Paralysis. Ann Neurol. 2000;47(1):46-53.

INDICATION AND IMPORTANT SAFETY INFORMATION — READ MORE

Indication and Important Safety Information

 

What is KEVEYIS?

KEVEYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.

 

What should you tell your healthcare provider before taking KEVEYIS?

Tell your doctor if you are allergic to dichlorphenamide or other sulfa drugs; if you take high doses of aspirin, or if you have lung or liver disease; if you are pregnant, plan to become pregnant, or are breastfeeding or plan to breastfeed.

 

What should you know about KEVEYIS?

  • Severe allergic and other reactions have happened with sulfonamides (drugs such as KEVEYIS) and have sometimes been fatal. Stop taking KEVEYIS at the first sign of skin rash, swelling, difficulty breathing, or any other unexpected side effect or reaction, and call 911 right away.
  • Tell your healthcare provider if you take aspirin or if another healthcare provider instructs you to begin taking aspirin. High doses of aspirin should not be taken with KEVEYIS.
  • KEVEYIS can cause your body to lose potassium, which can lead to heart problems. Your healthcare provider will measure the potassium levels in your blood before you start treatment and at certain times during treatment.
  • Tell your healthcare provider about all other prescription and over-the-counter medicines you take, including supplements, as some medicines can interact with KEVEYIS.
  • While taking KEVEYIS, your body may produce too much acid or may not be able to remove acid from the body. Your healthcare provider may run tests on a regular basis to check for signs of acid buildup.
  • KEVEYIS may increase your risk of falling. Tell your healthcare provider right away if you experience a fall while taking KEVEYIS.
  • The risks of falls and acid buildup are greater in elderly patients.
  • It is not known whether KEVEYIS is safe or effective for people younger than 18 years of age.

 

What are the most common side effects with KEVEYIS?

The most common side effects are a feeling of numbness, tingling or burning (“pins and needles”) in the toes, feet, hands or fingers; trouble with memory or thinking; feeling confused; and unpleasant taste in the mouth.

These are not all of the possible side effects of KEVEYIS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Full Prescribing Information.

Xeris

Keveyis®, Xeris Pharmaceuticals®, Xeris CareConnection™, PPP MentorConnect™, and their associated logos are trademarks owned by or licensed to Xeris Pharmaceuticals, Inc.

FOR PATIENTS

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Copyright © 2024 Xeris Pharmaceuticals, Inc. All rights reserved.
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Get customized support for your KEVEYIS journey. Simply fill out the information and a Patient Access Manager will contact you. They will walk you through the entire process, from diagnosis to treatment and beyond.

By submitting this form, I understand I am giving Xeris Pharmaceuticals, Inc., its affiliates, and business partners permission to use the personal information provided in this registration form to contact me by the following methods, but not limited to: mail, email, telephone call or in-person about disease and product information, disease or product-related events, support services, market research, and to share promotional and marketing information. By submitting this form, I consent to these uses and am confirming that I have read and agree to the Xeris Pharmaceuticals® Terms of Use and Privacy Statement. I understand I can unsubscribe by clicking on the unsubscribe link in future communications or by sending a letter with my full contact information (eg, name, address, email, phone, etc) to Xeris CareConnection™ Patient Support Services, 1375 W Fulton Street, Suite 1300, Chicago, IL 60607.

Thank you!

We’ve received your message and will be in touch shortly.