Finding out how KEVEYIS can help you
How has KEVEYIS been proven to treat PPP?
KEVEYIS has been shown to reduce the number, severity, and length of PPP episodes in 2 separate clinical studies.1,2
It is the only drug approved by the FDA for the treatment of PPP.1 Be sure to talk to your doctor about what you can expect when you start taking KEVEYIS.
Everyone who takes KEVEYIS has different treatment goals, so work with your doctor to decide on goals that are right for you—for example, reducing how many episodes you have. Be sure to check in with your doctor regularly so he or she can see if KEVEYIS is working for you.
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“Now I feel like I’ve been able to gain greater control over my condition—I don’t have to worry about coming down with bouts of weakness or paralysis as often as I used to.”
When compared with placebo (an inactive pill) in one study…2
KEVEYIS has been studied in 2 separate clinical studies and was proven to be an effective treatment for Primary Periodic Paralysis.1,2
Number of PPP episodes decreased |
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Episodes were shorter |
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Episodes were not as severe |
A second study confirmed the results of the first study.1
What are the most common side effects with KEVEYIS?
In the key clinical study, some of the most common side effects of KEVEYIS were1:
Tingling or prickling sensations (“pins and needles”)
Confusion or trouble paying attention
Changes in taste
Brain fog
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“After starting KEVEYIS, I did have some tingling in my fingers and lips. My vision was also a little blurry, but these side effects lasted a couple of days and went away on their own.”
How do you take KEVEYIS?
You take KEVEYIS by mouth once or twice daily, depending on what your doctor has prescribed.1
Your doctor determined how much KEVEYIS you should take every day based on your specific needs, which may be different from how much KEVEYIS someone else takes.1
Treatment with KEVEYIS is personalized, so your doctor can change your dose to find what’s right for you.1
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Indication and Important Safety Information
What is KEVEYIS?
KEVEYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.
What should you tell your healthcare provider before taking KEVEYIS?
Tell your doctor if you are allergic to dichlorphenamide or other sulfa drugs; if you take high doses of aspirin, or if you have lung or liver disease; if you are pregnant, plan to become pregnant, or are breastfeeding or plan to breastfeed.
What should you know about KEVEYIS?
- Severe allergic and other reactions have happened with sulfonamides (drugs such as KEVEYIS) and have sometimes been fatal. Stop taking KEVEYIS at the first sign of skin rash, swelling, difficulty breathing, or any other unexpected side effect or reaction, and call 911 right away.
- Tell your healthcare provider if you take aspirin or if another healthcare provider instructs you to begin taking aspirin. High doses of aspirin should not be taken with KEVEYIS.
- KEVEYIS can cause your body to lose potassium, which can lead to heart problems. Your healthcare provider will measure the potassium levels in your blood before you start treatment and at certain times during treatment.
- Tell your healthcare provider about all other prescription and over-the-counter medicines you take, including supplements, as some medicines can interact with KEVEYIS.
- While taking KEVEYIS, your body may produce too much acid or may not be able to remove acid from the body. Your healthcare provider may run tests on a regular basis to check for signs of acid buildup.
- KEVEYIS may increase your risk of falling. Tell your healthcare provider right away if you experience a fall while taking KEVEYIS.
- The risks of falls and acid buildup are greater in elderly patients.
- It is not known whether KEVEYIS is safe or effective for people younger than 18 years of age.
What are the most common side effects with KEVEYIS?
The most common side effects are a feeling of numbness, tingling or burning (“pins and needles”) in the toes, feet, hands or fingers; trouble with memory or thinking; feeling confused; and unpleasant taste in the mouth.
These are not all of the possible side effects of KEVEYIS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information.
References
- KEVEYIS [package insert]. Feasterville-Trevose, PA: Strongbridge Biopharma; 2019.
- Sansone VA, Burge J, McDermott MP, et al; for the Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology. 2016;86:1408-1416.