Manage your
Primary Periodic Paralysis
today — and in the future
PATIENT TESTIMONIAL
“For someone...with PPP, there really is hope. Things can be so much better once you have a treatment plan in place.”
Finding the right PPP treatment plan
You may face a lot of stress as you try to find a diagnosis and treatment plan for PPP. The good news is that developing a treatment plan focused on both today and the future can help.
Work with your doctor to find the best PPP treatment plan for you. Remember that your treatment plan should include long-term attack prevention strategies and guidance for managing episodes when they arise.1
The importance of reducing the number of PPP attacks
Therapeutic options that reduce the number of PPP episodes are recommended for long-term maintenance.1 Medications may help you gain more control over your PPP and engage more fully in life.
KEVEYIS is proven to help reduce the number, severity and length of PPP attacks.2,3
Know your triggers — and manage them
Certain factors, known as triggers, can cause a PPP episode.1 Learning to identify your triggers can help you better manage episodes. Common triggers include:
- Food or beverages high in salt, carbohydrates or potassium
- Stress or tiredness
- Becoming cold
- Periods of inactivity
- Resting after exercise
Treat an oncoming or current attack
You may be able to gain greater control over your PPP episodes using the tips below.1,4 Talk to your doctor about the best PPP management plan for you.
Hypokalemic Primary Periodic Paralysis (HypoPPP)
PPP episodes may involve a decrease in potassium levels.1,4
Take potassium supplements as recommended by a healthcare provider.1,4 Eat a low sodium, low carbohydrate diet
Hyperkalemic Primary Periodic Paralysis (HyperPPP)
Eat frequent carbohydrate-heavy meals.1,4 Avoid potassium-rich foods
Paramyotonia Congenita (PMC)
Attacks of muscle stiffness that occur during activity such as exercise5
Avoid cold temperatures and strenuous exercise4
Andersen-Tawil Syndrome (ATS)
Characterized by muscle weakness, changes in heartbeat, and distinct skeletal features.1,6 It is associated with low, normal, or high potassium levels during an episode
Light exercise may help decrease the severity of an episode6
PATIENT TESTIMONIAL
"Be patient with yourself, be forgiving... There are all sorts of help, advice, tools available to manage [PPP] and things will improve."
Keep track of your episodes
Use the Daily Tracker Tool to record details of your PPP episodes. This can help you determine if something is a trigger or if a management strategy is working. The tracker also includes a 1-Month Diary.
Stay up to date on PPP information
Access the latest information to help you gain more control over PPP.
References
- Statland JM, Fontaine B, Hanna MG, et al. Review of the diagnosis and treatment of periodic paralysis. Muscle Nerve. 2018;57:522-530.
- KEVEYIS [package insert]. Chicago, IL; Xeris Pharmaceuticals, Inc.
- Sansone VA, Burge J, McDermott MP, et al; for the Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology. 2016;86:1408-1416.
- Ralph J, Ptacek L. Muscle channelopathies: periodic paralyses and nondystrophic myotonias. In: Rosenberg RN, Pascual JM, eds. Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric Disease. 5th ed. Elsevier; 2015:1177- 1189.
- Paramyotonia Congenita. MedlinePlus. Updated August 1, 2015. Accessed June 10, 2025. https://medlineplus.gov/genetics/condition/paramyotonia-congenita/#causes
- Veerapandiyan A, Statland JM, Tawil R. Andersen-Tawil Syndrome. In: Adam MP, Ardinger HH, Pagon RA, et al, eds. GeneReviews®. University of Washington, Seattle; 1993-2019. Updated June 7, 2018. Accessed March 22, 2024. https://www.ncbi.nlm.nih.gov/books/NBK1264/
