Celebrating 10 years of PPP Support! See how we ensure you never walk alone here.
Celebrating 10 years of PPP Support!
Celebrating 10 years of PPP Support! See how we ensure you never walk alone here.
Celebrating 10 years of PPP Support!
Primary Periodic Paralysis (PPP) is a rare condition that impacts your muscles.1 It can cause episodes of muscle weakness or temporary paralysis, often brought on by triggers.
*Based on a study of 37 adults with HypoPPP that participated in a 3-year follow-up study observing their disease progression.
PPP is usually passed down from a parent to a child.1 However, you can still have PPP without an identified genetic connection if you have the signs and symptoms.
PPP causes recurrent and debilitating episodes of muscle weakness and temporary paralysis, negatively impacting your daily life.1,4
PPP episodes can vary in number, severity and length:1
In some people, episodes happen every day. For others, episodes occur weekly or monthly.
PPP episodes may involve weakness that limits some daily activities. More severe episodes can mean complete, but temporary, paralysis.
Most episodes last a few hours. In some cases, they can last for days.
“I usually became paralyzed in the middle of the night, so I would have to holler for my mom or sisters to help turn me because I would be in so much pain. I would have total feeling from head to toe, but couldn’t move a thing.”
The burden of PPP episodes is not only physical. Weakness, loss of energy and stiff muscles can limit your ability to engage in activities with friends and family, resulting in a serious impact on your emotional state.1,4
*Based on a survey of 66 self-selected patients over the age of 40 years with a clinical diagnosis of Primary Periodic Paralysis who sought support via the internet. Permanent muscle weakness was defined as muscle weakness which is always present and varies little from day-to-day.
There are several subtypes of PPP. What makes them different is the level of potassium in your blood during the episode, what happens during the episode, what triggers it, and which genes are involved.1,5,6
All types of PPP cause muscle weakness that can impact several parts of the body.1,4
PPP episodes may involve a decrease in potassium levels.
PPP episodes may involve an increase in potassium levels. In some cases, potassium levels are normal during an episode.
PPP episodes may involve normal or elevated potassium levels during an episode
*Patients with ATS were not included in clinical trials for KEVEYIS
PPP episodes can happen at any time — but they’re usually brought on by a trigger. Common triggers across the four PPP types may include:
Triggers can vary depending on your specific PPP diagnosis, as well as other factors.
Because of how rare PPP is, it can be challenging to receive an accurate diagnosis. Your symptoms may be confused for those of more common conditions, like mental health disorders such as depression.1,4
If PPP is suspected, your doctor may review your medical history and your family’s medical history, then perform a physical exam and blood tests.1 Your doctor may also recommend:
KEVEYIS (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.
For more information, see full Prescribing Information for KEVEYIS.
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